AI-enabled digital staining for Mohs surgery and dermatopathology
AI-enabled digital staining for Mohs surgery and dermatopathology
AI-enabled digital staining for Mohs surgery and dermatopathology
AI-enabled digital staining for Mohs surgery and dermatopathology
PathScience Direct-to-Digital Staining technology uses AI to convert scans of unstained tissue into familiar, pathologist-readable H&E-style images for digital pathology workflows, starting with Mohs surgery and dermatopathology.
PathScience Direct-to-Digital Staining technology uses AI to convert scans of unstained tissue into familiar, pathologist-readable H&E-style images for digital pathology workflows, starting with Mohs surgery and dermatopathology.
PathScience Direct-to-Digital Staining technology uses AI to convert scans of unstained tissue into familiar, pathologist-readable H&E-style images for digital pathology workflows, starting with Mohs surgery and dermatopathology.
What is Direct-to-Digital Staining?
What is Direct-to-Digital Staining?
Direct-to-Digital Staining is PathScience’s approach to generating digital stain images directly from unstained tissue. Instead of relying only on traditional chemical staining, PathScience applies AI models to scanned tissue images to create familiar H&E-style digital stains for pathologist review. Our initial focus is Mohs surgery and dermatopathology, where speed, tissue preservation, and workflow consistency are critical.
Direct-to-Digital Staining is PathScience’s approach to generating digital stain images directly from unstained tissue. Instead of relying only on traditional chemical staining, PathScience applies AI models to scanned tissue images to create familiar H&E-style digital stains for pathologist review. Our initial focus is Mohs surgery and dermatopathology, where speed, tissue preservation, and workflow consistency are critical.
PathScience Benefits
PathScience Benefits
PathScience Benefits
PathScience Benefits

1
1
Faster digital stain generation
Faster digital stain generation
Generate H&E-style digital stain images from unstained tissue scans in minutes, supporting faster review workflows for Mohs and dermatopathology teams.
2
2
Reduce chemical staining steps
Reduce chemical staining steps
Create digital stain images without the traditional reagent-heavy staining workflow.
3
3
Preserve more tissue for additional analysis
Preserve more tissue for additional analysis
Minimize destructive processing steps and keep more specimen material available for future stains or testing.
4
4
Designed for digital pathology workflows
Designed for digital pathology workflows
Use Direct-to-Digital Staining alongside existing scanning and digital review processes.
5
5
Familiar H&E-style appearance
Familiar H&E-style appearance
Produce recognizable digital images designed to match the visual language pathologists already use.
Built by pathology, AI, and medical imaging experts
Built by pathology, AI, and medical imaging experts
Built by pathology, AI, and medical imaging experts
PathScience is developing patented Direct-to-Digital Staining technology for digital pathology. Our team brings together clinical pathology, medical leadership, AI research, software engineering, and product development expertise.
PathScience is developing patented Direct-to-Digital Staining technology for digital pathology. Our team brings together clinical pathology, medical leadership, AI research, software engineering, and product development expertise.
Patented digital staining technology
Patented digital staining technology
Focused on Mohs surgery and dermatopathology
Focused on Mohs surgery and dermatopathology
H&E-style digital stain samples available at 40×
H&E-style digital stain samples available at 40×
Led by physicians, researchers, and software builders
Led by physicians, researchers, and software builders

Showcase
Showcase
Showcase
We create vibrant, recognizable clinical images that pathologists use in their existing workflows.
View our showcase to see samples of 40x H & E digital stains.
We create vibrant, recognizable clinical images that pathologists use in their existing workflows.
View our showcase to see samples of 40x H & E digital stains.
We create vibrant, recognizable clinical images that pathologists use in their existing workflows.
View our showcase to see samples of 40x H & E digital stains.

Discover our Latest News
Discover our Latest News
Discover our Latest News
Discover our Latest News
Questions About Digital Staining?
Questions About Digital Staining?
Questions About Digital Staining?
Questions About Digital Staining?
Explore how PathScience’s Direct-to-Digital Staining technology is designed to support digital pathology workflows by creating familiar H&E-style images from unstained tissue scans.
Explore how PathScience’s Direct-to-Digital Staining technology is designed to support digital pathology workflows by creating familiar H&E-style images from unstained tissue scans.
Explore how PathScience’s Direct-to-Digital Staining technology is designed to support digital pathology workflows by creating familiar H&E-style images from unstained tissue scans.
What is PathScience?
PathScience is a digital pathology company developing AI-enabled Direct-to-Digital Staining technology.
What is PathScience?
PathScience is a digital pathology company developing AI-enabled Direct-to-Digital Staining technology.
What is Direct-to-Digital Staining?
What is Direct-to-Digital Staining?
Who is PathScience built for?
Who is PathScience built for?
Does PathScience require traditional chemical staining?
Does PathScience require traditional chemical staining?
What kind of images does PathScience generate?
What kind of images does PathScience generate?
Bring Direct-to-Digital Staining into your workflow

Bring Direct-to-Digital Staining into your workflow
Bring Direct-to-Digital Staining into your workflow
Bring Direct-to-Digital Staining into your workflow
Bring Direct-to-Digital Staining into your workflow
Learn how PathScience can support Mohs surgery, dermatopathology, and digital pathology teams.
Learn how PathScience can support Mohs surgery, dermatopathology, and digital pathology teams.

© 2026 PathScience. All rights reserved.

© 2026 PathScience. All rights reserved.

© 2026 PathScience. All rights reserved.



